Structure-function relationships of glutamine synthetases |
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| Authors: | Eisenberg D Gill H S Pfluegl G M Rotstein S H |
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| Affiliation: | UCLA-DOE Laboratory of Structural Biology and Molecular Medicine, Departments of Chemistry, Biochemistry and Biological Chemistry, University of California, Los Angeles, 201 MBI, Box 951570, Los Angeles, CA 90095-1570, USA. david@mbi.ucla.edu |
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| Abstract: | As a highly regulated enzyme at the core of nitrogen metabolism, glutamine synthetase has been studied intensively. We review structural and functional studies of both bacterial and eukaryotic glutamine synthetases, with emphasis on enzymatic inhibitors. |
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