A comparison of lymphocyte antigen specificities in Norwegian and Swiss goats |
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| Authors: | L. L. NESSE ,G. RUFF&dagger |
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| Affiliation: | *Department of Microbiology and Immunology, Norwegian College of Veterinary Medicine, Oslo and National Veterinary Institute, Oslo, Norway;†Institute of Animal Breeding, Division of Immunogenetics, University of Berne, Switzerland |
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| Abstract: | Summary. In all, 363 alloantireagents were tested in Berne, Switzerland and in Oslo, Norway against lymphocytes from 1679 goats of different breeds. The same lymphocytotoxicity test was used at both laboratories. The test data were pooled, and correlation coefficients for pairs of sera were used to group the sera in clusters. Twelve clusters were accepted as defining lymphocyte antigen specificities believed to be coded by genes within the major histocompatibility complex (MHC). The specificities defined by these clusters were designated Eu 1-Eu12. Two clusters defined specificities which were not coded from loci within the MHC. These were designated GLY-1.1 and GLY-2.1, and the loci GLY-1 and GLY-2, respectively. GLY-1.1 was also located on erythrocytes. |
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| Keywords: | goat major histocompatibility complex MHC GLA GLY |
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