Utilization of 1-chloromethylsilatrane by Rhodotorula mucilaginosa |
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Authors: | Fattakhova AN Ofitserov EN Diyakov VM Naumova RP |
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Institution: | Department of Microbiology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima, Japan |
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Abstract: | Abstract The imperfect yeast, Rhodotorula mucilaginosa utilized nitrogen of 1-chloromethylsilatrane (CMS) as a sole nitrogen source when grown on glucose, glycerol, methanol, ethanol and succinate. Under such conditions and at concentrations from 0.45 to 4.5 mM, CMS was a growth-limiting factor. Atomic absorption spectrometry revealed the accumulation of silicon compounds in the cultural liquid which were chloroform-insoluble in contrast to CMS. The following pathway of the partial decomposition of CMS is propoposed: CMS → chloromethylsilanethryol → bis(chloromethyldisiloxane) tetraol. |
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Keywords: | Clostridium perfringens epsilon toxin (Histidyl residue) |
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