Peripheral arterial disease in polymyalgia rheumatica |
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Authors: | Frances A Borg Bhaskar Dasgupta |
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Institution: | 1. Department of Rheumatology, Southend University Hospital, Prittlewell Chase, Westcliffe-on-Sea, Essex, SS0 0RY, UK
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Abstract: | Patients with polymyalgia rheumatica have been shown to have an increased risk of peripheral arterial disease on longitudinal
follow-up. Possible explanations for this include premature atherosclerosis related to chronic inflammation, as with other
inflammatory rheumatological conditions. Alternatively, polymyalgia rheumatica can be associated with vasculitis, even in
the absence of clinical giant cell arteritis, and peripheral vascular disease may represent subclinical vasculitis. Further
work is required to elucidate the reasons for this increased risk. Currently, it would remain reasonable to aggressively control
modifiable atherosclerotic risk factors. |
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Keywords: | |
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