高危孕妇胎儿缺氧与彩色多普勒超声结合四维超声检查的相关性研究

摘要 目的：探讨与研究高危孕妇胎儿缺氧与彩色多普勒超声结合四维超声检查的相关性。方法：2018年2月到2020年1月在本院进行建档分娩的高危孕妇108例作为研究对象，都给予彩色多普勒超声结合四维超声检查，记录影像学特征，判定胎儿缺氧发生情况并进行相关性分析。结果：在高危孕妇108例中，发生宫内缺氧28例（宫内缺氧组），发生率为25.9 %；宫内缺氧组的大脑中动脉、脐动脉的阻力指数（RI）、搏动指数（PI）、收缩期峰值流速舒张期流速比值（S/D）均高于非宫内缺氧组（P<0.05）；宫内缺氧组的上腔静脉血流心室收缩期峰值流速（S波）、心房收缩期速度（A波）、心室舒张期峰值流速（D波）均高于非宫内缺氧组（P<0.05）；高危孕妇108例中，Spearsman分析显示大脑中动脉、脐动脉的RI、PI、S/D以及上腔静脉血流S、D、A均与宫内缺氧都存在相关性（P<0.05）；logistic多因素回归分析显示：大脑中动脉、脐动脉的S/D与上腔静脉血流S、A为导致胎儿缺氧的主要影响因素（P<0.05）。结论：高危孕妇胎儿缺氧与彩色多普勒超声结合四维超声检查特征具有相关性，彩色多普勒超声结合四维超声可作为检查胎儿缺氧的可行、简单无创、方便快捷的方式，具有极高的应用价值。

Correlation Study of High-risk Pregnant Women with Fetal Hypoxia and Color Doppler Ultrasound Combined with Four-dimensional Ultrasound

ABSTRACT Objective: To explore and study the correlation between high-risk pregnant women and fetal hypoxia and color Doppler ultrasound combined with four-dimensional ultrasound. Methods: February 2018 to January 2020, 108 cases of high-risk pregnant women who were filed deliveries in our hospital were selected. All the cases were all given color Doppler ultrasound combined with four-dimensional ultrasound, recorded the imaging characteristics and determined the occurrence of fetal hypoxia. And carried out correlation analysis. Results: There were 28 cases of intrauterine hypoxia occurred (intrauterine hypoxia group) in the 108 cases, the incidence were 25.9 %. The resistance index (RI), pulsation index (PI), the peak systolic flow velocity and the diastolic flow velocity ratio (S/D) of the middle cerebral artery and the umbilical artery in the intrauterine hypoxia group were higher than those of the non-intrauterine hypoxia group(P<0.05). The superior vena cava blood flow ventricular systolic peak velocity (S wave), atrial systolic velocity (a wave) and ventricular diastolic peak flow velocity (D wave) in the intrauterine hypoxia group were higher than those in the non-intrauterine hypoxia group(P<0.05). In the 108 high-risk pregnant women, Spearsman analysis showed that the RI, PI, S/D of the middle cerebral artery and umbilical artery, blood flow S, D, A of the superior vena cava were correlated with the intrauterine hypoxia(P<0.05). The logistic multivariate regression analysis showed that the S/D of the middle cerebral artery and the umbilical artery and the blood flow of the superior vena cava S and A were the main influencing factors of fetal hypoxia(P<0.05). Conclusion: Fetal hypoxia in high-risk pregnant women are correlated with the characteristics of color Doppler ultrasound combined with four-dimensional ultrasound. Color Doppler ultrasound combined with four-dimensional ultrasound can be feasible, simple, non-invasive, convenient and quick way to detect fetal hypoxia, and have very good application values.