负压封闭引流技术对颈部及躯干深度烧伤植皮修复患儿生活质量和血清炎症因子的影响

摘要 目的：观察负压封闭引流技术（VSD）对颈部及躯干深度烧伤植皮修复患儿生活质量和血清炎症因子的影响。方法：选取2016年4月~2020年12月期间我院接收的颈部及躯干深度烧伤患儿70例，采用计算机系统随机编号的方式将患儿分为2组，分别为对照组35例和实验组35例。对照组患儿进行游离植皮后常规包扎处理，实验组患儿进行游离植皮后在VSD下进行包扎处理。考察两组患儿疗效指标。术前、出院后30 d采用36项健康调查简表（SF-36）评估所有患儿的生活质量。术前、术后7d观察两组炎症因子水平变化。记录两组患儿并发症发生率。结果：实验组术后7 d植皮成功率高于对照组，术后住院天数、术后创面愈合时间短于对照组，术后换药次数少于对照组（P<0.05）。出院后30 d，两组患儿生理功能(PF)、总体健康 (GH)、生理职能(RP)、活力 (VT)、躯体疼痛(BP)、情感职能 (RE)、社会功能(SF)及精神健康(MH)评分均较术前升高，且实验组高于对照组（P<0.05）。术后7 d，两组患儿血清白介素-6（IL-6）、C 反应蛋白（CRP）和降钙素原（PCT）水平均较术前降低，且实验组低于对照组（P<0.05）。实验组的并发症总发生率低于对照组（P<0.05）。结论：针对颈部及躯干深度烧伤植皮修复患儿，在VSD下进行包扎处理，可提高植皮成功率，缩短住院天数及创面愈合时间，减少换药次数，降低并发症发生率，还可提高患儿生活质量及减轻机体炎性反应，值得临床借鉴。

The Effect of Vacuum Sealing Drainage on the Quality of Life and Serum Inflammatory Factors in Children with Deep Neck and Trunk Burn Skin Grafting for Repair

ABSTRACT Objective: To observe the effect of vacuum sealing drainage (VSD) on the quality of life and serum inflammatory factors in children with deep neck and trunk burn skin grafting for repair. Methods: 70 cases of deep burn of neck and trunk who were received by our hospital from April 2016 to December 2020 were selected. The children were divided into two groups by computer system random number, 35 in control group and 35 in experimental group. The control group was treated with routine wrapping after free skin grafting, and the experimental group was treated with VSD after free skin grafting. The curative effect indexes of the two groups were investigated. Before operation and 30d after discharge, 36 health surveys summary list (SF-36) were used to evaluate the quality of life of children in the two groups. The changes of serum inflammatory factors in the two groups were observed before and 7 d after operation, and the incidence of complications in the two groups were recorded. Results: The success rate of skin grafting at 7 d after operation in the experimental group was higher than that of the control group, the days of hospitalization after operation and wound healing time after operation were shorter than those of the control group, the number of dressing changes after operation was less than that of the control group (P<0.05). 30 d after discharge, the scores of physiological function (PF), general health (GH), physiological function (RP), vitality (VT), body pain (BP), emotional function (RE), social function (SF) and mental health (MH) were higher than those before operation, and the experimental group was higher than the control group (P<0.05). 7 d after operation, the levels of serum interleukin-6(IL-6), C-reactive protein (CRP) and procalcitonin (PCT) in two groups were lower than those before operation, and the experimental group was lower than the control group(P<0.05). The total incidence of complications in the experimental group was lower than that of the control group (P<0.05). Conclusion: For the children with deep neck and trunk burn skin grafting for repair, the wrapping treatment under VSD can improve the success rate of skin grafting, shorten the days of hospitalization and wound healing time, reduce the number of dressing changes, reduce the incidence of complications, improve the quality of life of children and reduce the inflammatory response of the body, which is worthy of clinical reference.