全氟显4D-HyCoSy与3D-HyCoSy对输卵管性不孕症患者的诊断效果评价

摘要 目的：探讨与评价全氟显子宫输卵管四维超声造影（4D-HyCoSy）与经阴道三维超声输卵管造影（3D-HyCoSy）对输卵管性不孕症患者的诊断效果。方法：选择2018年8月到2021年11月选择在本院诊治的女性不孕症患者84例作为研究对象，都给予全氟显4D-HyCoSy与3D-HyCoSy诊断，记录图像质量与不良反应发生情况。金标准为腹腔镜检查，判断诊断效果。结果：在84例患者中，全氟显4D-HyCoSy的图像质量优良率为100.0 %，高于3D-HyCoSy的92.9 %（P<0.05）。全氟显4D-HyCoSy诊断为输卵管通畅14例，输卵管通而不畅23例，输卵管阻塞47例。3D-HyCoSy诊断：22例输卵管通畅，21例输卵管通而不畅，41例输卵管阻塞。腹腔镜诊断：15例输卵管通畅，21例输卵管通而不畅，48例输卵管阻塞。全氟显4D-HyCoSy、3D-HyCoSy对输卵管性不孕症患者的诊断敏感性为100.0 %（36/36）、97.2 %（35/36），特异性为97.9 %（47/48）、83.3 %（40/48）。84例患者在全氟显4D-HyCoSy、3D-HyCoSy检查期间发生的不良反应主要为阴道出血、恶心呕吐、腹部疼痛等，不良反应发生率对比无差异（P>0.05）。全氟显4D-HyCoSy对输卵管性不孕症患者的诊断敏感性与3D-HyCoSy对比无差异（P>0.05），诊断特异性高于3D-HyCoSy（P<0.05）。结论：相对于3D-HyCoSy，全氟显4D-HyCoSy在输卵管性不孕症患者的应用能提高图像质量优良率，具有很好的安全性，还具有更好的诊断特异性。

Evaluation of Diagnostic Efficacy of Fluorocarbon with 4D-HyCoSy and 3D-HyCoSy for Tubal Infertility

ABSTRACT Objective: To explore and evaluate the diagnostic effect of perfluorinated hysterosalpingography four-dimensional sonography (4D-HyCoSy) and transvaginal three-dimensional sonography (3D-HyCoSy) in patients with tubal infertility. Methods: From August 2018 to November 2021, A total of 84 cases of female infertility patients who were diagnosed and treated in our hospital were selected as the research subjects. All of them were diagnosed with perfluorinated 4D-HyCoSy and 3D-HyCoSy, and the image quality and the occurrence of untoward effect were recorded. Laparoscopy were used as the gold standard for diagnosis to determine the diagnostic effect. Results: The image quality rate of perfluorinated 4D-HyCoSy were 100.0 %, which were higher than 92.9 % of 3D-HyCoSy (P<0.05) in the 84 patients. Perfluorinated 4D-HyCoSy diagnosed 14 cases of tubal patency, 23 cases of tubal patency and 47 cases of tubal obstruction. 3D-HyCoSy diagnosed 22 cases of tubal patency, 21 cases of tubal obstruction, and 41 cases of tubal obstruction. Laparoscopic diagnosis were 15 cases of tubal patency, 21 cases of tubal obstruction, and 48 cases of tubal obstruction. The diagnostic sensitivity of perfluorinated 4D-HyCoSy and 3D-HyCoSy for tubal infertility patients were 100.0 % (36/36), 97.2 % (35/36), and the specificity were 97.9 % (47/48) and 83.3 %(40/48). The adverse reactions of 84 patients during the examination of PFOS 4D-HyCoSy and 3D-HyCoSy were no difference in the incidence of untoward effect (P>0.05). Compared with 3D-HyCoSy, the diagnostic sensitivity of perfluorinated 4D-HyCoSy in patients with tubal infertility were not different(P>0.05), and the diagnostic specificity were higher than that of 3D-HyCoSy(P<0.05). Conclusion: Compares with 3D-HyCoSy, the application of perfluorinated 4D-HyCoSy in patients with tubal infertility can improve the image quality rate, it has good safety, and has better diagnostic specificity.