Histone propinquity using imidoesters. |
| |
Authors: | R Chalkley |
| |
Affiliation: | Department of Biochemistry University of Iowa, Iowa City, Iowa 52242 USA |
| |
Abstract: | Native chromatin was reacted with bifunctional protein cross-linking reagents of varying molecular sizes. Short cross-linkers do not produce significant yields of polymeric histones whereas intermediate-sized materials such as dimethyladipimidate produce extensive interaction between histones. Dimethylsuberimidate reacts with all histone fractions but only generates polymers of F1 and of F2b and F2a2. |
| |
Keywords: | |
本文献已被 ScienceDirect 等数据库收录! |