| 甘草药材上的污染真菌类群及其产毒素特性 |
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| 引用本文： | 陈娟,杨蕾,蔡飞,杨美华,高微微. 甘草药材上的污染真菌类群及其产毒素特性[J]. 菌物学报, 2010, 29(3): 335-339 |
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| 作者姓名： | 陈娟 杨蕾 蔡飞 杨美华 高微微 |
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| 作者单位： | 中国医学科学院北京协和医学院药用植物研究所,北京,100193 |
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| 基金项目： | 科技部“重大新药创制”科技重大专项（No. 2009ZX09502-025-01）；国家中医药管理局中医药行业科研专项（No. 200807042） |
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| 摘 要： | 对药材市场上霉变甘草样品的污染真菌进行分析,共得到4属7种真菌,包括Penicillium、Aspergillus、Fusarium、Mucor属,其中Penicillium polonicum、Aspergillus parasiticus以及P.crustosum是优势真菌。采用高效液相色谱-质谱联用技术对优势菌菌株产黄曲霉毒素及赭曲霉毒素A的特性进行检测。结果表明A.parasiticus主要产生黄曲霉毒素(AFG2、AFG1、AFB2、AFB1)和赭曲霉毒素A(OTA);而Penicillium polonicum主要产生赭曲霉毒素A(OTA)。
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| 关 键 词： | 污染真菌，黄曲霉毒素，赭曲霉毒素A |
Fungi associated with Glycyrrhiza uralensis and their capability of mycotoxin production |
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| CHEN Juan,YANG Lei,CAI Fei,YANG Mei-Hua and GAO Wei-Wei. Fungi associated with Glycyrrhiza uralensis and their capability of mycotoxin production[J]. Mycosystema, 2010, 29(3): 335-339 |
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| Authors: | CHEN Juan YANG Lei CAI Fei YANG Mei-Hua GAO Wei-Wei |
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| Affiliation: | Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China |
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| Abstract: | Mouldiness of medicinal herbs occurred commonly during storage. Fungi associated with mouldy materials of Glycyrrhiza uralensis and their capability of mycotoxin production were investigated. Medicinal materials of G. uralensis were collected from herbal markets. Seven fungal species belonging to Penicillium, Aspergillus, Fusarium and Mucor were isolated. Among them, Penicillium polonicum, Aspergillus parasiticus and P. crustosum were dominant. Mycotoxin production was detected by HPLC-MS technique. Aspergillus parasiticus produced aflatoxins (AFG2, AFG1, AFB2, AFB1) and ochrotoxin A (OTA), while Penicillium polonicum mainly produced ochrotoxin A (OTA). |
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| Keywords: | toxigenic fungi aflatoxins ochrotoxin A |
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