首页 | 本学科首页   官方微博 | 高级检索  
   检索      


Characterization and In Vivo Pharmacological Rescue of a Wnt2-Gata6 Pathway Required for Cardiac Inflow Tract Development
Authors:Ying Tian  Lijun Yuan  Ashley M Goss  Tao Wang  Jifu Yang  John J Lepore  Diane Zhou  Robert J Schwartz  Vickas Patel  Ethan David Cohen  Edward E Morrisey
Institution:1. Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA;2. Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA 19104, USA;3. Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA 19104, USA;4. Institute for Regenerative Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA;5. Department of Ultrasound Diagnostics, Tangdu Hospital, Fourth Military Medical University, Xi''an, Shanxxi, 710032, China;6. Institute of Biosciences and Technology, Texas A & M Health Science Center, Houston, TX 77030, USA
Abstract:
><ol class=
  • Download : Download high-res image (150KB)
  • Download : Download full-size image
  • Highlights? Wnt2 is required for atrial and inflow tract morphogenesis ? Wnt2 regulates expansion of secondary heart field progenitors ? Defects in Wnt2?/? mutants can be rescued using Wnt signaling agonists ? Wnt2 cooperates with Gata6 to regulate cardiac inflow tract development
    Keywords:
    本文献已被 ScienceDirect 等数据库收录!
    设为首页 | 免责声明 | 关于勤云 | 加入收藏

    Copyright©北京勤云科技发展有限公司  京ICP备09084417号