首页 | 本学科首页   官方微博 | 高级检索  
   检索      


Organism-Scale Modeling of Early Drosophila Patterning via Bone Morphogenetic Proteins
Authors:David M Umulis  Osamu Shimmi  Michael B O'Connor  Hans G Othmer
Institution:1. Agricultural and Biological Engineering, Weldon School of Biomedical Engineering, and Bindley Bioscience Center, 225 South University Street, Purdue University, West Lafayette, IN 47907, USA;2. Institute of Biotechnology, University of Helsinki, 00014 Helsinki, Finland;3. Howard Hughes Medical Institute, and Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, MN 55455, USA;4. School of Mathematics and Digital Technology Center, University of Minnesota, Minneapolis, MN 55455, USA
Abstract:
><ol class=
  • Download : Download high-res image (265KB)
  • Download : Download full-size image
  • Highlights? Capturing 3D spatiotemporal content of expression data increases model utility ? Embryo geometry shapes signaling; prepatterns compensate in misshapen embryos ? Cell-surface binding proteins compensate for weak ligand/inhibitor/receptor binding ? BMP-mediated patterning is “nearly” scale-invariant
    Keywords:
    本文献已被 ScienceDirect 等数据库收录!
    设为首页 | 免责声明 | 关于勤云 | 加入收藏

    Copyright©北京勤云科技发展有限公司  京ICP备09084417号