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Metformin,Independent of AMPK,Inhibits mTORC1 in a Rag GTPase-Dependent Manner
Authors:Adem Kalender  Anand Selvaraj  So Young Kim  Pawan Gulati  Sophie Brûlé  Benoit Viollet  Bruce E Kemp  Nabeel Bardeesy  Patrick Dennis  John J Schlager  André Marette  Sara C Kozma  George Thomas
Institution:1. Department of Cancer and Cell Biology, Metabolic Diseases Institute, University of Cincinnati, 2180 E. Galbraith Road, Cincinnati, OH 45237, USA;2. Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, 4058 Basel, Switzerland;3. Dana-Farber Cancer Institute, Department of Medical Oncology, 44 Binney Street, D1537, Boston, MA 02115, USA;4. Department of Anatomy and Physiology, Laval University Hospital Research Center, Ste-Foy, QC G1V 4G5, Canada;5. Lipid Research Unit, Laval University Hospital Research Center, Ste-Foy, QC G1V 4G5, Canada;6. Institut Cochin, Université Paris Descartes, CNRS, UMR 8104, Paris F-75014, France;7. INSERM, U567, Paris-75014, France;8. St. Vincent''s Institute of Medical Research, University of Melbourne, 41 Victoria Parade, Fitzroy, Victoria 3065, Australia;9. Massachusetts General Hospital, Center for Cancer Research, Simches Building, CPZN 4200, 185 Cambridge Street, Boston, MA 02114, USA;10. Human Effectiveness Directorate, Air Force Research Laboratory, Wright-Patterson Air Force Base, Dayton, OH 45433, USA
Abstract:
Keywords:
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