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Analysis of the Glutathione S-Transferase P1 Gene Ile105Val Polymorphism in the Patients with Sporadic Motor Neuron Disease from Russia |
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| Authors: | Zherebtsova A. L. Shadrina M. I. Levitsky G. N. Levitskaya N. I. Alekhin A. V. Slominsky P. A. Skvortsova V. I. Limborska S. A. |
| Affiliation: | (1) Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, 123182, Russia;(2) Department of Fundamental and Clinical Neurology, Russian State Medical University, Moscow, 129327, Russia |
| Abstract: | Ile105Val polymorphism in exon 5 of glutathione S-transferase (GSTP1) gene was examined in a group of patients with motor neuron disease (MND) and control sample. No statistically significant differences in the allele and genotype frequency distributions between the samples examined were demonstrated. We conclude that Ile105Val polymorphism is not associated with the risk of the disease development in the patients from Russia with sporadic form of MND. |
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