Unexpected presence of defective glpR alleles in various strains of Escherichia coli |
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| Authors: | Holtman C K Thurlkill R Pettigrew D W |
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| Affiliation: | Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas 77843-2128, USA. |
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| Abstract: | Alleles of glpR associated with the same GlpR(-) phenotype produce substitutions in different conserved portions of the glycerol 3-phosphate repressor which are not part of the helix-turn-helix motif. Analysis of the effects on growth and enzyme expression show that glucose repression of glycerol utilization is not dependent on a functional repressor. |
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