The study of interaction between paralogous tandem repeats stellate and suppressor of stellate in the genome of Drosophila melanogaster |
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Authors: | Aravin A A Naumova N M Tulin A V Klenov M S Gvozdev V A |
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Affiliation: | Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, Russia. |
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Abstract: | Testis-specific expression of tandemly repeated Stellate genes, located in eu- and heterochromatin regions of the X chromosome of Drosophila melanogaster, is suppressed by homologous Suppressor of Stellate repeats located on the Y chromosome. Using transgenic lines, we have demonstrated that three Su(Ste) copies failed to change the expression of the reporter construction carrying the bacterial beta-galactosidase gene under control of the Stellate gene regulatory sequence. Possible mechanisms of the Su(Ste) repeat suppressor activity are discussed. |
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