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Dual-mode Imaging of Cutaneous Tissue Oxygenation and Vascular Function
Authors:Ronald X Xu  Kun Huang  Ruogu Qin  Jiwei Huang  Jeff S Xu  Liya Ding  Urmila S Gnyawali  Gayle M Gordillo  Surya C Gnyawali  Chandan K Sen
Institution:1.Department of Biomedical Engineering, The Ohio State University;2.Department of Biomedical Informatics, The Ohio State University;3.Comprehensive Wound Center, The Ohio State University;4.Department of Surgery, The Ohio State University
Abstract:Accurate assessment of cutaneous tissue oxygenation and vascular function is important for appropriate detection, staging, and treatment of many health disorders such as chronic wounds. We report the development of a dual-mode imaging system for non-invasive and non-contact imaging of cutaneous tissue oxygenation and vascular function. The imaging system integrated an infrared camera, a CCD camera, a liquid crystal tunable filter and a high intensity fiber light source. A Labview interface was programmed for equipment control, synchronization, image acquisition, processing, and visualization. Multispectral images captured by the CCD camera were used to reconstruct the tissue oxygenation map. Dynamic thermographic images captured by the infrared camera were used to reconstruct the vascular function map. Cutaneous tissue oxygenation and vascular function images were co-registered through fiduciary markers. The performance characteristics of the dual-mode image system were tested in humans.
Keywords:Medicine  Issue 46  Dual-mode  multispectral imaging  infrared imaging  cutaneous tissue oxygenation  vascular function  co-registration  wound healing
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