Shared Y chromosome repetitive DNA sequences in stallion and donkey as visualized using whole-genomic comparative hybridization |
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| Authors: | J Gosálvez F Crespo JL Vega-Pla C López-Fernández EI Cortés-Gutiérrez MI Devila-Rodriguez R Mezzanotte |
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| Institution: | 1.Department of Biology, Genetics Unit, Universidad Autonoma de Madrid (UAM), Madrid, Spain;;2.Veterinary Services of the Spanish Army (FESCCR-Ministerio de Defensa), Avila, Spain;;3.Department of Genetics, Northwest Research Centre of Biology, Mexican National Institute for Health, Monterrey, Mexico;;4.Department of Biomedical Sciences and Biotechnology, Section of Genetics, Cittadella Universitaria, Monserrato (Cagliari), Italy |
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| Abstract: | The genome of stallion (Spanish breed) and donkey (Spanish endemic Zamorano-Leonés) were compared using whole comparative genomic in situ hybridization (W-CGH) technique, with special reference to the variability observed in the Y chromosome. Results show that these diverging genomes still share some highly repetitive DNA families localized in pericentromeric regions and, in the particular case of the Y chromosome, a sub-family of highly repeated DNA sequences, greatly expanded in the donkey genome, accounts for a large part of the chromatin in the stallion Y chromosome.Key words: mammalian genome, mammalian cytogenetics, genome evolution, comparative genomics. |
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