Synthesis and Biological Evaluation of a Series of New Cyclohexenyl Nucleosides |
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Abstract: | Abstract A series of cyclohexenyl nucleosides (1–8) were successfully prepared with moderate yield and their cytotoxicity and antiviral activity were investigated. Among the eight new compounds, only the diaminopurine analogue 8 showed pronounced activity against HSV-1, HSV-2. |
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