坐式八段锦联合运动康复治疗对急性冠脉综合征PCI术后患者运动耐力、血清心肌损伤标志物和生活质量的影响

摘要 目的：探讨坐式八段锦联合运动康复治疗对急性冠脉综合征（ACS）经皮冠状动脉介入治疗术（PCI）后患者运动耐力、血清心肌损伤标志物和生活质量的影响。方法：根据随机数字表法，将我院2020年4月~2021年5月期间收治的ACS行PCI术的患者（n=120）分为对照组（运动康复治疗，n=60）和研究组（坐式八段锦联合运动康复治疗，n=60）。对比两组心功能指标[左心室舒张末期内径（LVEDD）、左心室射血分数（LVEF）、氨基末端B型脑利钠肽前体（NT-proBNP）、左心室舒张末期容积（LVEDV）]、心肌损伤标志物[肌酸激酶同工酶（CK-MB）、心肌肌钙蛋白I（cTnI）]、运动耐力指标[无氧阈（AT）、最大摄氧量（VO_2max ）、运动持续时间（ED）]和生活质量[西雅图心绞痛量表（SAQ）评分：躯体活动受限程度（PL）、心绞痛稳定情况（AS）、疾病认知程度（DS）、心绞痛发作状况（AF）和治疗满意程度（TS）]，并纪录两组不良心血管事件发生情况。结果：研究组的心血管不良事件发生率低于对照组（P<0.05）。研究组治疗3个月后LVEF高于对照组，LVEDD、LVEDV、NT-proBNP低于对照组（P<0.05）。研究组治疗3个月后CK-MB、cTnI低于对照组（P<0.05）。研究组治疗3个月后AT、VO_2max 、ED高于对照组（P<0.05）。研究组治疗3个月后PL、AS、DS、AF、TS评分高于对照组（P<0.05）。结论：坐式八段锦联合运动康复治疗可促进ACS患者PCI术后心功能改善，减轻心肌损伤，进而提高运动耐力和生活质量。

Effects of Sitting Baduanjin Combined with Exercise Rehabilitation Therapy on Exercise Tolerance, Serum Myocardial Injury Markers and Quality of Life in Patients with Acute Coronary Syndrome after PCI

ABSTRACT Objective: To investigate the effect of sitting Baduanjin combined with exercise rehabilitation therapy on exercise tolerance, serum myocardial injury markers and quality of life of patients with acute coronary syndrome (ACS) after percutaneous coronary intervention (PCI). Methods: According to the method of random number table, the patients with ACS undergoing PCI in our hospital from April 2020 to May 2021 (n=120) were divided into the control group (exercise rehabilitation therapy, n=60) and the research group (sitting Baduanjin combined exercise rehabilitation therapy, n=60). The patients in the control group received exercise rehabilitation therapy, and the patients in the study group received sitting Baduanjin combined exercise rehabilitation therapy. The cardiac function indexes [left ventricular end diastolic diameter (LVEDD), left ventricular ejection fraction (LVEF), N-terminal precursor of B-type brain natriuretic peptide (NT-proBNP), left ventricular end diastolic volume (LVEDV)], myocardial injury markers [creatine kinase isoenzyme (CK-MB), cardiac troponin I (cTnI)] exercise tolerance indexes [anaerobic threshold (AT), maximum oxygen uptake (VO_2max ), exercise duration (ED)] and quality of life [Seattle Angina Questionnaire (SAQ) score: physical activity limitation (PL), angina stability (AS), disease cognition (DS), angina attack (AF) and treatment satisfaction (TS)] in the two groups were compared, and the occurrence of adverse cardiovascular events in the two groups were recorded. Results: The incidence of adverse cardiovascular events in the study group was lower than that in the control group (P<0.05). LVEF in the study group was higher than that in the control group after 3 months of treatment, and LVEDD, LVEDV, NT-proBNP were lower than those in the control group (P<0.05). CK-MB and cTnI in the study group were lower than those in the control group after 3 months of treatment (P<0.05). AT, VO_2max and ED in the study group were higher than those in the control group after 3 months of treatment (P<0.05). The scores of PL, AS, DS, AF, TS in the study group were higher than those in the control group after 3 months of treatment (P<0.05). Conclusion: Sitting Baduanjin combined with exercise rehabilitation therapy can promote the improvement of cardiac function in patients with ACS after PCI, reduce myocardial injury, and improve exercise endurance and quality of life.