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Synthesis of olean-18(19)-ene derivatives from betulin
Authors:O. B. Flekhter  N. I. Medvedeva  G.A. Tolstikov  F. Z. Galin  M. S. Yunusov  Huong Nguen Thi Mai  Le Viet Tien  I. V. Savinova  E. I. Boreko  L. P. Titov  I. V. Glukhov
Affiliation:1. Institute of Organic Chemistry, Ufa Scientific Center, Russian Academy of Sciences, pr. Oktyabrya 71, Ufa, 450054, Bashkortostan, Russia
2. Research Center of Applied Chemistry, Biological Sciences, and Biotechnologies, University of Natural Sciences, Vietnam National University, Ho Chi Minh City, Vietnam
3. Research Institute of Epidemiology and Microbiology, Ministry of Health of Republic Belarus, Minsk, Republic Belarus
4. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Moscow, Russia
Abstract:The rare olean-18(19)-ene triterpenoids moradiol and moronic acid were synthesized from betulin, and their antiviral properties were investigated.
Keywords:antiviral activity  betulin  lupane and oleanane type triterpenoids  moronic acid  X-ray analysis
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