Oligomycin sensitivity-conferring protein (OSCP) of beef heart mitochondria. Internal sequence homology and structural relationship with other proteins |
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| Authors: | N N Ovchinnikov YuA Y" >Modyanov,V A Grinkevich,N A Aldanova,P V Kostetsky,O E Trubetskaya,T Hundal,L Ernster |
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| Affiliation: | 1. Shemyakin Institute of Biorganic Chemistry, USSR Academy of Sciences, Moscow, 117312 USSR;2. Department of Biochemistry, Arrhenius Laboratory, University of Stockholm, S-106 91 Stockholm, Sweden |
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| Abstract: | Structural analysis of oligomycin sensitivity-conferring protein (OSCP) revealed repeating sequences (residues 1-89, 105-190) suggesting an evolution of the protein by gene duplication. In addition to the reported homology with the delta-subunit of Escherichia coli F1ATPase, OSCP also shows a certain homology with the b-subunit of E. coli F0 and the ADP/ATP carrier of mitochondria. |
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| Keywords: | Oligomycin sensitivity-conferring protein Subunit Sequence homology Structural relationship Comparative analysis |
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