Genetic variants of serum alpha-1-antitrypsin (Pi types) in a Breton population, the Bigoudens |
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Authors: | P Youinou A Gueguen J P Martin J Jouquan D Salmon J Ruffie G Le Menn C Salmon |
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Abstract: | Pi typing was carried out by high resolution isoelectric focusing in 397 Bigoudens and in 100 non-Bigouden Bretons. Gene frequencies were computed by the gene counting method. No difference between the two groups could be demonstrated, neither was there a deviation from the expected Hardy-Weinberg distribution nor a heterogeneity between the Bigouden villages. The results were significantly different (p less than 0.02) from those reported in Normans. |
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