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Relationship between body adiposity measures and risk of primary knee and hip replacement for osteoarthritis: a prospective cohort study
Authors:Yuanyuan Wang  Julie Anne Simpson  Anita E Wluka  Andrew J Teichtahl  Dallas R English  Graham G Giles  Stephen Graves and Flavia M Cicuttini
Institution:(1) Department of Epidemiology and Preventive Medicine, Monash University, Central and Eastern Clinical School, Alfred Hospital, Melbourne, VIC, 3004, Australia;(2) Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, School of Population Health, University of Melbourne, Carlton, VIC, 3053, Australia;(3) Cancer Epidemiology Centre, The Cancer Council Victoria, Carlton, VIC, 3053, Australia;(4) Baker Heart Research Institute, Commercial Road, Melbourne, VIC, 3004, Australia;(5) Department of Orthopaedic Surgery, University of Melbourne, Royal Melbourne Hospital, Parkville, VIC, 3050, Australia;(6) AOA National Joint Replacement Registry, Discipline of Public Health, School of Population Health & Clinical Practice, University of Adelaide, SA, 5005, Australia
Abstract:

Introduction  

Total joint replacement is considered a surrogate measure for symptomatic end-stage osteoarthritis. It is unknown whether the adipose mass and the distribution of adipose mass are associated with the risk of primary knee and hip replacement for osteoarthritis. The aim of the present investigation was to examine this in a cohort study.
Keywords:
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