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Analysis of the mouseAmy locus in recombinant inbred mouse strains
Authors:Palash R. Paul  Rosemary W. Elliott
Affiliation:(1) Department of Molecular and Cellular Biology, Roswell Park Memorial Institute, 666 Elm Street, 14263 Buffalo, New York;(2) Present address: Department of Cell Biology, Roche Institute of Molecular Biology, 07110 Nutley, New Jersey
Abstract:Pancreatic and salivary amylase cDNA probes have been used to search for new DNA fragment length variation among a total of 43 inbred mouse strains. Fragment length differences found with three restriction endonucleases grouped the strains into two major classes. The segregation of these variant fragments has been analyzed among several sets of recombinant inbred strains and is presented here. Previously reported differences for strains YBR and CE have been confirmed. New segregation data for carbonic anhydrase, a locus near the proximal end of mouse chromosome 3, are presented.
Keywords:amylase  DNA variation (fragment length)  recombinant inbred strains  linkage map  carbonic anhydrase  mouse chromosome 3
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