Variation in ribosomal RNA gene number in mouse chromosomes |
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Authors: | Henderson A S Eicher E M Yu M T Atwood K C |
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Institution: | Department of Human Genetics and Development, College of Physicians and Surgeons of Columbia University, New York, NY, USA. |
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Abstract: | Hybridization of 125-I-ribosomal RNA to mouse chromosomes in situ produced significant differences in grain count at known rDNA sites, depending on the strains from which they were derived. This is interpreted to mean that the number of rRNA genes in a given nucleolar chromosome, and in the entire genome, is polymorphic among strains and among outbred individuals. |
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