Synthesis of the nuclear protein cyclin does not correlate directly with transformation in quail embryo fibroblasts

The synthesis of the nuclear protein 'cyclin' (MW 36 000) has been analysed in several virus-transformed quail embryo fibroblasts (QEF) by means of quantitative two-dimensional gel electrophoresis. Our studies revealed that the synthesis of cyclin does not correlate directly with cell transformation, but with cell proliferation.