Cellular immune responses in Huntington's disease (H.D.). Detection of H.D. and multiple sclerosis (M.S.) brain antigenicity by H.D. but not M.S. lymphocytes. |
| |
| Authors: | D S Barkley S I Hardiwidjaja J H Menkes G W Ellison L W Myers |
| |
| Institution: | 1. Department of Pathology, UCLA Center for the Health Sciences Los Angeles, California 90024 U.S.A.;2. Department of Psychiatry, Cedars-Sinai Medical Center Los Angeles, California 90024 U.S.A.;3. Department of Neurology, Brentwood Veterans Administration Hospital, Los Angeles, California 90024 U.S.A. |
| |
| Abstract: | Lymphocytes from patients with Huntington's disease (H.D.) exhibit a cellular immune response which consists of two components: a minor component directed against antigen common to all human brains, and a major component directed against antigen found thus far only in H.D. and multiple sclerosis (M.S.) gray matter. M.S. lymphocytes exhibit a response to antigen common to all human brains, but fail to show any H.D. or M.S. brain-specific response. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
