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Isocitrate Dehydrogenase (IDH) Mutations Promote a Reversible ZEB1/MicroRNA (miR)-200-dependent Epithelial-Mesenchymal Transition (EMT)
Authors:Alexandra R Grassian  Fallon Lin  Rosemary Barrett  Yue Liu  Wei Jiang  Manav Korpal  Holly Astley  Daniel Gitterman  Thomas Henley  Rob Howes  Julian Levell  Joshua M Korn  Raymond Pagliarini
Institution:From the Novartis Institutes for Biomedical Research, Cambridge, Massachusetts 02139 and ;§Horizon Discovery Ltd., 7100 Cambridge Research Park, Waterbeach, Cambridge, CB25 9TL, United Kingdom
Abstract:
Keywords:Cancer Biology  Cell Metabolism  EMT  Oncogene  Signal Transduction  Tumor Cell Biology  Tumor Metabolism
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