Extracellular <Emphasis Type="Italic">Paracoccidioides brasiliensis</Emphasis> phospholipase B involvement in alveolar macrophage interaction |
| |
| Authors: | Deyze Alencar Soares Rosângela Vieira de Andrade Simoneide Sousa Silva Anamélia Lorenzetti Bocca Sueli Maria Soares Felipe Silvana Petrofeza |
| |
| Institution: | 1.Instituto de Ciências Biológicas,Universidade Federal de Goiás,Goiania,Brazil;2.Programa de Pós-gradua??o em Ciências Gen?micas e Biotecnologia,Universidade Católica de Brasília,Brasília,Brazil;3.Departamento de Biologia Celular,Universidade de Brasília,Brasília,Brazil |
| |
| Abstract: | Background Phospholipase B (PLB) has been reported to be one of the virulence factors for human pathogenic fungi and has also been described
as necessary for the early events in infection. Based on these data, we investigated the role of PLB in virulence and modulation
of the alveolar pulmonary immune response during infection using an in-vitro model of host-pathogen interaction, i.e. Paracoccidioides brasiliensis yeast cells infecting alveolar macrophage (MH-S) cells. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
