Ragged--a new rexoid mutant rat with large sebaceous gland

A new hair defected mutant rat was established. This mutant was covered with ragged hair since about 10 days of age, then transiently lost most of hair in the back at approximately 5 weeks of age and re-covered with ragged hair thereafter. Thickened eyerids occurred since about 3 weeks of age. Histological examination revealed enlarged sebaceous glands with greater number of sebaceous cells in the back skin. The oil stained skin samples showed normal sebaceous transformation and pilosebaceous canal. Genetical analysis showed that the ragged hair character was a single recessive trait and indicated that this single recessive gene was not linked with the coat color genes, non-agouti (a), albino (c) and hooded (h). From the present data and previous reports, we recommended this single recessive gene is a new rexoid mutation thereby we termed this gene "Ragged (rg)".