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Fluorinated peptide nucleic acid |
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| Authors: | Hollenstein Marcel Gautschi Daniel Leumann Christian J |
| Affiliation: | Department of Chemistry and Biochemistry, University of Bern, Bern, Switzerland. hollenstein@ioc.unibe.ch |
| Abstract: | The fluorinated olefinic peptide nucleic acid analogue (F-OPA) monomer containing the base thymine was synthesised in 13 steps. PNAs containing this unit were prepared and their pairing properties assessed by means of UV-melting experiments. |
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