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Design and synthesis of A3 adenosine receptor ligands, 2'-fluoro analogues of Cl-IB-MECA |
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| Authors: | Kim Hea Ok Park Jae Gyu Moon Hyung Ryong Gunaga Prashantha Lim Moo Hong Chun Moon Woo Jacobson Kenneth A Kim Hee-Doo Jeong Lak Shin |
| Institution: | Division of Chemistry and Molecular Engineering, Seoul National University, Seoul, South Korea. |
| Abstract: | Synthesis of 2'-deoxy-2'-fluoro-N6-substituted adenosines as bioisosteres of Cl-IB-MECA and their binding affinities to A3 adenosine receptor are described. |
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