Synthesis of a base-protected xylo-LNA adenine nucleoside |
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| Authors: | Bryld Torsten Wengel Jesper |
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| Institution: | Nucleic Acid Center, Department of Chemistry, University of Southern Denmark, Odense M, Denmark. |
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| Abstract: | Synthesis of (1S,3R,4R,7R)-7-hydroxy-1-hydroxymethyl-3-(6-N-benzoyl-adenin-9-yl)-2,5-dioxabicyclo2.2.1]heptane (2), a base-protected xylo-LNA adenine nucleoside, has been accomplished using a convergent synthetic strategy starting from 1,2-di-O-acetylfuranose 3. |
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