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Olefinic peptide nucleic acid (OPA)
Authors:Gautschi Daniel  Leumann Christian J
Institution:Department of Chemistry and Biochemistry, University of Bern, Bern, Switzerland.
Abstract:The olefinic peptide nucleic acid analogues (OPA) monomers containing the bases thymine and adenine were synthesised in 11 steps. Fully modified oligomers containing these units were prepared and their pairing properties assessed by means of UV-melting experiments.
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