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A novel and convenient method for the synthesis of free 5'-thiol modified oligonucleotides |
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| Authors: | Kupihár Z Kovács G Kele Z Darula Z Kovács L |
| Affiliation: | Nucleic Acids Laboratory, Department of Medicinal Chemistry, University of Szeged, Szeged, Hungary. kupi@ovrisc.mdche.u-szeged.hu |
| Abstract: | The synthesis of free 5'-thiol-modified oligonucleotides using a 4,4',4'-trimethoxytrityl (TMTr)-protected linker and standard Poly-Pak purification has been described. |
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