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Improved synthesis of 2'-amino-LNA |
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| Authors: | Christensen Signe M Rosenbohm Christoph Sørensen Mads Larsen Lotte-Emilie Wengel Jesper Koch Troels |
| Affiliation: | Cureon A/S, Copenhagen, Denmark. smc@cureon.com |
| Abstract: | 2'-Amino-LNA phosphoramidite (10) was synthesised by means of a new strategy, which is convergent with the synthesis of 2'-oxy-LNA up until a late stage intermediate (1). |
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