Studies on the biosynthesis of ralfuranones in Ralstonia solanacearum |
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| Authors: | Kenji Kai Hideyuki Ohnishi Akinori Kiba Kouhei Ohnishi Yasufumi Hikichi |
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| Affiliation: | 1. Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Osaka, Japan;2. Laboratory of Plant Pathology and Biotechnology, Kochi University, Kochi, Japan;3. Research Institute of Molecular Genetics, Kochi University, Kochi, Japan |
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| Abstract: | Ralfuranones, aryl-furanone secondary metabolites, are involved in the virulence of Ralstonia solanacearum in solanaceous plants. Ralfuranone I (6) has been suggested as a biosynthetic precursor for other ralfuranones; however, this conversion has not been confirmed. We herein investigate the biosynthesis of ralfuranones using feeding experiments with ralfuranone I (6) and its putative metabolite, ralfuranone B (2). The results obtained demonstrated that the biosynthesis of ralfuranones proceeded in enzymatic and non-enzymatic manners. |
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| Keywords: | ralfuranones biosynthesis furanone synthase quorum sensing Ralstonia solanacearum |
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