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Cytotoxicity of CdSe-based quantum dots incorporated in glass nanoparticles evaluated using human keratinocyte HaCaT cells
Authors:Masanori Ando  Masanori Horie  Yoko Akazawa-Ogawa  Yoshihisa Hagihara  Norio Murase
Affiliation:1. Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST) , Ikeda, Japan;2. Health Research Institute, National Institute of Advanced Industrial Science and Technology (AIST) , Ikeda, Japan;3. Research Institute of Electrochemical Energy, National Institute of Advanced Industrial Science and Technology (AIST) , Ikeda, Japan
Abstract:CdSe quantum dots (QDs) are potential fluorescent reagents, but leakage of Cd and Se often induces cytotoxicity. Here we prepared CdSe-based QDs with glass to reduce their leakage and examined their cytotoxicity using keratinocyte cells. The cytotoxicity of the QDs with glass was obviously lower than that of the commercial QDs with polymer, suggesting their safety for biological applications.
Keywords:CdSe  cytotoxicity  glass  polymer  quantum dot
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