Lactococcus lactis subsp. lactis JCM 5805 activates natural killer cells via dendritic cells |
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| Authors: | Hiroaki Suzuki Konomi Ohshio Daisuke Fujiwara |
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| Affiliation: | Central Laboratories for Key Technologies, Kirin Co., Ltd., Yokohama, Japan |
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| Abstract: | Lactococcus lactis subsp. lactis JCM 5805 (JCM5805) has been shown to stimulate plasmacytoid dendritic cells (pDC). Here, we investigated the effect of JCM5805 on NK cells. In vitro studies suggested that JCM5805 activated natural killer (NK) cells via dendritic cells including pDC. Furthermore, the oral administration of JCM5805 enhanced the cytotoxic activity of NK cells |
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| Keywords: | natural killer cells dendritic cells Lactococcus lactis |
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