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Activation of MEK1/ERK1/2/iNOS/sGC/PKG pathway associated with peroxynitrite formation contributes to hypotension and vascular hyporeactivity in endotoxemic rats
Authors:Belma Korkmaz  Kemal Buharalioglu  Seyhan Sahan-Firat  Tuba Cuez  A Tuncay Demiryurek  Bahar Tunctan  
Institution:a Department of Pharmacology, Faculty of Pharmacy, Mersin University, Mersin, Turkey;b Department of Pharmacology, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey
Abstract:
Keywords:Endotoxin  Hypotension  Vascular hyporeactivity  MEK1/ERK1/2/iNOS/sGC/PKG pathway  Peroxynitrite
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