| Abstract: | The number of lymphocytes, immunoblasts, plasmoblasts and plasmocytes was counted in the tissues of the couch of the skin grafts transplanted at 8 a. m., 4 and 24 p. m. Sixty-six, 76 and 86 hours after operation the differences were significant in the number of lymphocytes and plasmocytes, whereas after 136, 146 and 156 hours in the quantity of all cells under study. This indicates the influence of the circadian phase of the body on the course and intensity of cell and tissue reactions seen during graft rejection. A preliminary conclusion is drawn that 8 a. m. is a less favourable time for performing skin allotransplantation in mice, whereas 4 p. m. is a more favorable time. |
