Ivermectin resistant and susceptible third-stage larvae of Haemonchus contortus: cholinesterase and phosphatase activities |
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| Authors: | Giménez-Pardo Consuelo Martínez-Grueiro Maria Mercedes Gómez-Barrio Alicia Rodríguez-Caabeiro Filomena |
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| Affiliation: | Departamento de Microbiología y Parasitología, Facultad de Farmacia, Universidad de Alcalá, Ctra, Madrid-Barcelona km 33, 28871 Alcalá de Henares, Madrid, Espa?a. consuelo.gimenez@uah.es |
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| Abstract: | Cholinesterase and acid phosphatase (AP), but not alkaline phosphatase activities, were detected in cytosolic and membrane-bound fractions of ivermectin resistant and susceptible Haemonchus contortus infective-stage larvae. Some differences in acetylcholinesterase activity of cytosolic fractions and in the AP activity of these fractions as well as in the response to AP inhibitors by membrane-bound fractions were detected. Data are discussed. |
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