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Free choline formation by cerebral cortical slices from rat brain
Authors:E T Browning
Affiliation:1. Department of Fisheries and Marine Bioscience, Jashore University of Science and Technology, Jashore 7408, Bangladesh;2. Department of Fisheries and Marine Bioscience, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj 8100, Bangladesh;3. Department of Agro Product Processing Technology, Jashore University of Science and Technology, Jashore 7408, Bangladesh;4. Department of Food Science and Technology, Pukyong National University, Busan, 48-513, Republic of Korea;1. National-Local Joint Engineering Laboratory of Breeding and Cultivation of Edible and Medicinal Fungi, Sichuan Institute of Edible Fungi, Sichuan Academy of Agricultural Sciences, Chengdu 610066, China;2. Key Laboratory of Bio-resources and Eco-environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, China;3. School of Bioengineering, Jiangnan University, Wuxi 214122, China;1. College of Environmental and Resource Sciences, Zhejiang University, Zhejiang Provincial Key Laboratory of Agricultural Resources and Environment, Hangzhou, Zhejiang 310058, China;2. Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore;3. NUS Environmental Research Institute (NERI), #02-01, T-Lab Building (TL), 5A Engineering Drive 1, Singapore 117411, Singapore
Abstract:Changes in free choline levels of cerebral cortical slices and their incubation fluid were examined under conditions of active ACh synthesis. Free choline was found to increase tenfold during two hours of incubation. Most of the free choline, which was presumably formed from esterified choline precursors, was found in the extracellular medium.
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