Analysis of protein contacts into Protein Units |
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| Authors: | Guilhem Faure,Auré lie Bornot,Alexandre G. de Brevern |
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| Affiliation: | 1. INSERM UMR-S 726, Equipe de Bioinformatique Génomique et Moléculaire (EBGM), DSIMB, Université Paris Diderot - Paris 7, case 7113, 2 place Jussieu, 75251 Paris, France;2. INSERM UMR-S 665, Dynamique des Structures et Interactions des Macromolécules Biologiques (DSIMB), Université Paris Diderot - Paris 7, Institut National de Transfusion Sanguine (INTS), 6 rue Alexandre Cabanel, 75739 Paris cedex 15, France |
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| Abstract: | Three-dimensional structures of proteins are the support of their biological functions. Their folds are maintained by inter-residue interactions which are one of the main focuses to understand the mechanisms of protein folding and stability. Furthermore, protein structures can be composed of single or multiple functional domains that can fold and function independently. Hence, dividing a protein into domains is useful for obtaining an accurate structure and function determination. |
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| Keywords: | Amino acid Protein domain Side-chains Secondary structures Protein contacts Protein extremities Structural alphabet Protein Blocks |
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