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Diagnostics of thyroid cancer: Limitations of the existing methods and perspectives for future developments |
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| Authors: | N. P. Sharova I. R. Sumedi T. M. Astakhova A. S. Plekhanova Y. V. Lyupina E. E. Shashova I. V. Kondakova G. V. Rodoman |
| Affiliation: | 1. Koltzov Institute of Developmental Biology, Russian Academy of Sciences, ul. Vavilova 26, Moscow, 119334, Russia 2. Pirogov Russian National Research Medical University, ul. Ostrovityanova 1, Moscow, 117997, Russia 3. Tomsk Cancer Research Institute, Siberian Branch, Russian Academy of Medical Sciences, per. Kooperativnyi 5, Tomsk, 634009, Russia |
| Abstract: | A novel approach to the development of a precise method of intraoperative diagnostics of thyroid cancer has been proposed on the basis of fundamental study of proteasomes in malignant tumors of mammals and human. The method is based on estimation of proteasome activity in small fragments of the tumor and adjacent tissues. |
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