金黄色葡萄球菌溶血素的研究进展

金黄色葡萄球菌简称金葡菌，是一类革兰阳性需氧或兼性厌氧菌，可导致化脓性感染、肺炎、伪膜性肠炎、心包炎等局部感染，以及败血症、脓毒血症等全身感染。金黄色葡萄球菌的致病力强弱主要取决其产生的毒素和侵袭性酶，其中溶血素已经成为该细菌的一个重要致病因子。本文对金黄色葡萄球菌溶血素的分子特征、作用机制、免疫预防及临床应用方面的研究进展进行综述。

Hemolysin from Staphylococcus aureus: Research progress

Staphylococcus aureus is a gram-positive aerobic or facultative anaerobic bacteria which can lead to pyogenic infection, pneumonia, pseudomembranous colitis, pericarditis, and septicemia or sepsis shock. The pathogenicity of Staphylococcus aureus mainly depends on its toxins and invasive enzymes, among which hemolysin has become an important pathogenic factor of the bacteria. This article is a review on the molecular characteristics, mechanisms of action, immune prevention and clinical application of hemolysin from Staphylococcus aureus.