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Untargeted proteomics reveals upregulation of stress response pathways during CHO-based monoclonal antibody manufacturing process leading to disulfide bond reduction |
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| Authors: | Seo-Young Park Susan Egan Anthony J Cura Kathryn L Aron Xuankuo Xu Mengyuan Zheng Michael Borys Sanchayita Ghose Zhengjian Li Kyongbum Lee |
| Institution: | aDepartment of Chemical and Biological Engineering, Tufts University, Medford, MA, USA;bSchool of Chemical Engineering, Sungkyunkwan University, Suwon, Republic of Korea;cBiologics Development, Global Product Development and Supply, Bristol-Myers Squibb, Devens, USA |
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