A complete NMR spectral assignment of the conserved region of the MESD protein, MESD(12-155) |
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| Authors: | Jianglei Chen Guojun Bu Jianjun Wang |
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| Affiliation: | (1) Department of Biochemistry and Molecular Biology, School of Medicine, Wayne State University, Detroit, MI 48201, USA;(2) Departments of Pediatrics, and of Cell Biology and Physiology, Washington University School of Medicine, CB 8208, St. Louis, MO 63110, USA |
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| Abstract: | The low-density lipoprotein (LDL) receptor family members control diverse developmental and physiological pathways. Mesoderm development (MESD) protein is a 195-residue protein that functions as a specialized molecular chaperone to promote the proper folding of the six-bladed β-propeller/EGF modules of the LDL receptor family members. Here we report a complete NMR spectral assignment of the most conserved region of MESD protein, MESD(12-155). |
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| Keywords: | MESD LDL receptor Specialized chaperone Protein folding |
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