| Calcium, a signaling molecule in the endoplasmic reticulum? |
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| 引用本文： | Corbett EF,Michalak M. Calcium, a signaling molecule in the endoplasmic reticulum?[J]. Trends in biochemical sciences, 2000, 25(7): 307-311. DOI: 10.1016/S0968-0004(00)01588-7 |
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| 作者姓名： | Corbett EF Michalak M |
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| 摘 要： |
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Calcium,a signaling molecule in the endoplasmic reticulum? |
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| Corbett E F,Michalak M. Calcium,a signaling molecule in the endoplasmic reticulum?[J]. Trends in biochemical sciences, 2000, 25(7): 307-311. DOI: 10.1016/S0968-0004(00)01588-7 |
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| Authors: | Corbett E F Michalak M |
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| Affiliation: | MRC Group in Molecular Biology of Membranes and the Department of Biochemistry, University of Alberta, Edmonton, AL, Canada T6G 2H7. |
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| Abstract: | For many years now, it has been known that Ca2+ is an important signaling molecule in the cytosol of the cell, but emerging evidence suggests that Ca2+ might also play a signaling role in the endoplasmic reticulum. For example, agonist-induced fluctuations in free Ca2+ concentration in the endoplasmic reticulum can affect many functions of the endoplasmic reticulum, including protein synthesis and modification, and interchaperone interactions. |
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