Primary squamous cell carcinoma of the breast: A rare case report |
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Authors: | Stefania Carbone Rosabel Lobo Alvarez Annalisa Lamacchia Asuncion Almenar Gil Raquel Martin Hernandez Jose Luis Lopez Guerra Hugo Marsiglia |
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Institution: | 1. Department of Radiation Oncology, Instituto Madrileño de Oncologia/Grupo IMO, Madrid, Spain;2. Department of Radiation Oncology, Instituto Oncologico de Castilla La Mancha/Grupo IMO, Toledo, Spain;3. Department of Radiation Oncology, University of Bari, Bari, Italy;4. Department of Radiology, Hospital Virgen de la Salud, Toledo, Spain;5. Department of Pathology, Hospital Virgen de la Salud, Toledo, Spain;6. Department of Radiation Oncology, Institut de cancérologie Gustave Roussy, Villejuif, Paris, France |
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Abstract: | BackgroundSquamous cells are normally not found inside the breast. Therefore, a primary squamous cell carcinoma of the breast is an exceptional phenomenon and the management of this type of disease is still debated.AimClinical outcome assessment of a patient with squamous cell carcinoma of the breast.Materials and methodsWe report a case of primary squamous cell carcinoma of the breast (T1cN0M0) in a 51-years-old woman who underwent breast conserving surgery plus adjuvant chemotherapy and radiation therapy (RT).ResultsWith a follow up of 43 months, the patient is alive with no evidence of local or distant recurrence. The patient had Grade 2 acute skin toxicity. No late skin or respiratory toxicity was observed.ConclusionsPure primary squamous cell carcinoma of the breast is a rare and aggressive disease, often treatment-refractory. Our case shows that the addition of RT after breast conserving surgery, allows to achieve a high local control without adding severe toxicity. A multidisciplinary approach seems to be the optimal management for early stages in this rare disease. |
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Keywords: | Squamous cell carcinoma Breast cancer Outcome |
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